Description

The Department of Physics and Astronomy at Clemson University invites applications for a Postdoctoral Fellow position in Biophysics under the mentorship of Assistant Professor Dr. Sheng Liu.

This position focuses on the development of a high-resolution single-particle tracking system based on MINFLUX microscopy to study protein dynamics and interactions in live cells. The successful candidate will play a central role in advanced instrumentation development and interdisciplinary biophysics research.

Primary research responsibilities include:

• Design, construction, and optimization of a MINFLUX microscope
• Development of instrument control software
• Data acquisition, processing, and quantitative analysis
• Preparation of manuscripts and grant proposals

Additional responsibilities may include:

• Cell line generation and biological sample preparation
• Development of data analysis algorithms for single-molecule and super-resolution data

Appointment Details

• Anticipated start date: September 1, 2026 (negotiable)
• Initial appointment: One year
• Renewal: Potential renewal based on performance and availability of funding

About Us: 

For more information about Clemson, please visit the website http://www.clemson.edu/. 

For more information about the department and its programs, please visit the website https://www.clemson.edu/science/academics/departments/physics/. 

For more information about Dr. Sheng Liu’s lab, please visit the website https://liulabclemson.github.io/labwebsite/.

Requirements

Required:

PhD in Optics, Physics, Electrical and Computer Engineering, Biomedical Engineering, or a closely related field, awarded or expected by 2026.

Preferred Experience:

• Optical system design and alignment
• Instrument control software development
• Electronic circuit design and FPGA programming
• Cell culture and biological sample preparation

Preferred Programming and Software Skills:

• Julia, Python, MATLAB, CUDA, LabVIEW
• Zemax, Inventor, SolidWorks
• KiCad, Vivado, or related tools

Application Instructions:

Review of applications will begin immediately; however, the position will remain open until filled.

Applicants should submit the following items via Interfolio at https://apply.interfolio.com/186637. 

• Cover letter describing research interests and past research experience
• Curriculum vitae, including publication list
• Names and contact information for three professional references

For more information, please contact Dr. Sheng Liu at shengl@clemson.edu.

Equal Employment Opportunity Statement:

Clemson University is an EEO/AA employer. Employment decisions are made without regard to characteristics protected by applicable law including disability and protected veteran status.